Multiple sulfur (δ³⁴S_sulfate, Δ³³S_sulfate, & Δ³⁶S_sulfate), nitrogen and oxygen (δ¹⁵N_nitrate & δ¹⁸O_nitrate) and strontium (⁸⁷Sr/⁸⁶Sr) isotope compositions of precipitation collected from Seoul, South Korea were analyzed to study the sources, transportation and deposition of air pollutants in East Asia. The δ³⁴S_sulfate values (from 1.9 to 14.6‰ with a median of 4.7‰) and the δ¹⁵N_nitrate values (from −2.0 to 13.3‰ with a median of 1.0‰) suggest that fossil fuel use (emission from coal combustion and vehicle exhaust) is a predominant source for sulfur and nitrogen, but other natural sources including biogenic contributions of DMS also add to their total budget. The seasonal variations are observed in δ³⁴S_sulfate and δ¹⁵N_nitrate values (both higher in winter season), which is likely to result from the increase of coal use for domestic heating in China. The δ¹⁸O_nitrate values also varied seasonally depending on the NO_x oxidation pathway, being about 20‰ higher in winter than in summer season. The Δ³³S_sulfate and Δ³⁶S_sulfate values are not anomalous, showing the absence of MIF signals in precipitation of Seoul. The ⁸⁷Sr/⁸⁶Sr ratio of the precipitation samples range from 0.70988 to 0.71487 with a median of 0.71073, indicating the influence of at least three end-member (silicate dust, carbonate dust and anthropogenic emission). Ionic ratios such as (K⁺+NH₄⁺)/(Ca²⁺+Mg²⁺) and Cl⁻/Na⁺ suggest the overwhelming effect of anthropogenic input rather than carbonate dust on the end-member with lower ⁸⁷Sr/⁸⁶Sr ratios.