Stroke is the second leading cause of death and disability worldwide and its diagnosis, and assessment of prognosis, remains challenging. There is a need for improved diagnostic and prognostic biomarkers. MicroRNAs (miRNAs) play important roles in the post-transcriptional regulation of gene expression and their secretion and remarkable stability in biofluids highlights their potential as sensitive biomarkers in the diagnosis and prognosis of acute stroke.

中文翻译：

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急性卒中的诊断和预后循环 MicroRNA：对当前证据的系统和生物信息学分析。

中风是全球第二大死亡和残疾原因，其诊断和预后评估仍然具有挑战性。需要改进的诊断和预后生物标志物。MicroRNAs (miRNAs) 在基因表达及其分泌的转录后调控中发挥重要作用，在生物体液中的显着稳定性突出了它们作为急性中风诊断和预后的敏感生物标志物的潜力。