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How does cervical spinal cord injury impact the cardiopulmonary response to exercise?
Respiratory Physiology & Neurobiology ( IF 2.3 ) Pub Date : 2021-06-09 , DOI: 10.1016/j.resp.2021.103714
C M Gee 1 , N D Eves 2 , A W Sheel 3 , C R West 4
Affiliation  

We compared cardiopulmonary responses to arm-ergometry in individuals with cervical spinal cord injury (C-SCI) and able-bodied controls. We hypothesized that individuals with C-SCI would have higher respiratory frequency (fb) but lower tidal volume (VT) at a given work rate and dynamically hyperinflate during exercise, whereas able-bodied individuals would not. Participants completed pulmonary function testing, an arm-ergometry test to exhaustion, and a sub-maximal exercise test consisting of four-minute stages at 20, 40, 60, and 80% peak work rate. Able-bodied individuals completed a further sub-maximal test with absolute work rate matched to C-SCI. During work rate matched sub-maximal exercise, C-SCI had smaller VT (main effect p < 0.001) compensated by an increased fb (main effect p = 0.009). C-SCI had increased end-expiratory lung volume at 80% peak work rate vs. rest (p < 0.003), whereas able-bodied did not. In conclusion, during arm-ergometry, individuals with C-SCI exhibit altered ventilatory patterns characterized by reduced VT, higher fb, and dynamic hyperinflation that may contribute to the observed reduced aerobic exercise capacity.



中文翻译:

颈脊髓损伤如何影响心肺对运动的反应?

我们比较了颈脊髓损伤 (C-SCI) 和健全对照个体对手臂测力计的心肺反应。我们假设患有 C-SCI 的个体在给定的工作速率下会有更高的呼吸频率 ( f b ) 但潮气量 (VT) 会更低,并且在运动期间会动态过度充气,而身体健全的个体则不会。参与者完成了肺功能测试、力竭的手臂测力测试以及由 20%、40%、60% 和 80% 峰值工作率的四分钟阶段组成的次最大运动测试。身体健全的人完成了进一步的次最大测试,绝对工作率与 C-SCI 相匹配。在工作速率匹配的次最大运动期间,C-SCI 具有较小的 VT(主效应 p < 0.001),由f b增加补偿(主效应 p = 0.009)。与休息相比,C-SCI 在 80% 的峰值工作率下增加了呼气末肺容量(p < 0.003),而身体健全者则没有。总之,在手臂测功期间,患有 C-SCI 的个体表现出改变的通气模式,其特征是 VT 降低、f b升高和动态过度充气,这可能导致观察到的有氧运动能力降低。

更新日期:2021-06-13
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