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Tomographic imaging with Compton PET modules: ideal case and first implementation
Journal of Instrumentation ( IF 1.3 ) Pub Date : 2021-04-30 , DOI: 10.1088/1748-0221/16/04/t04007
P Peng 1 , M Zhang 1 , N Zeraatkar 1 , J Qi 1 , S R Cherry 1
Affiliation  

In our previous studies, we demonstrated that the Compton PET module, a layer structure PET detector with side readout, can provide high performance in terms of spatial/energy/timing resolution, as well as high gamma ray detection efficiency. In this study, we investigate how to translate the high performance of the detector module into good quality reconstructed tomographic images. This study is performed using GATE simulation, as well as with physical experiments. Similar detector geometry is used in the simulation and experiment: two identical 4-layer detector modules are placed with face to face distance of 56 mm. In the simulation study, each layer consists of a 1-mm-pitch pixelated crystal array. In the experimental study, each layer is a monolithic crystal, which is virtually binned into 1 mm^2 cells to group single events according to the gamma ray interaction locations. A customized Derenzo phantom was placed between the two detector modules. By rotating the phantom using a motorized rotary stage, data along lines of response (LORs) at different angles were collected for reconstructing the tomographic image. The same reconstruction algorithm was used for both simulation and experimental studies. The results demonstrate that the simulation study could resolve 0.8 mm rods while the experimental study was able to resolve 1.0 mm rods.



中文翻译:

使用康普顿 PET 模块的断层成像:理想案例和首次实施

在我们之前的研究中,我们证明了康普顿 PET 模块,一种具有侧面读出功能的层状结构 PET 探测器,可以在空间/能量/时间分辨率方面提供高性能,以及高伽马射线探测效率。在这项研究中,我们研究了如何将检测器模块的高性能转化为高质量的重建断层扫描图像。本研究使用 GATE 模拟以及物理实验进行。模拟和实验中使用了类似的探测器几何结构:两个相同的 4 层探测器模块以 56 mm 的面对面距离放置。在模拟研究中,每一层都由一个 1 毫米间距的像素化晶体阵列组成。在实验研究中,每一层都是单片晶体,它实际上被分成 1 mm^2 单元,以根据伽马射线相互作用位置对单个事件进行分组。在两个检测器模块之间放置了一个定制的 Derenzo 体模。通过使用电动旋转台旋转体模,沿不同角度的响应线 (LOR) 收集数据以重建断层图像。相同的重建算法用于模拟和实验研究。结果表明,模拟研究可以解析 0.8 mm 的棒,而实验研究能够解析 1.0 mm 的棒。收集沿不同角度的响应线 (LOR) 的数据用于重建断层扫描图像。相同的重建算法用于模拟和实验研究。结果表明,模拟研究可以解析 0.8 mm 的棒,而实验研究能够解析 1.0 mm 的棒。收集沿不同角度的响应线 (LOR) 的数据用于重建断层扫描图像。相同的重建算法用于模拟和实验研究。结果表明,模拟研究可以解析 0.8 mm 的棒,而实验研究能够解析 1.0 mm 的棒。

更新日期:2021-04-30
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