Vacuum UV radiation from laser-induced plasma is used to ionise volatile organic compounds (VOCs) released by living organisms during their mass spectrometric analysis at atmospheric pressure without sample preparation. It is shown that the probability of ionisation of organic compounds with different ionisation potentials and proton affinity at atmospheric pressure in the argon flow weakly depends on the compound parameters and can be 3.6 10⁻⁵ – 1.4 10⁻⁴. The VOC spectra of mouse and human biological fluids are obtained without sample preparation at room temperature of the sample. The possibility of using the proposed method for the diagnosis of pathological changes is demonstrated.

来自激光诱导等离子体的真空紫外辐射用于电离活生物体在大气压下进行质谱分析期间释放的挥发性有机化合物 (VOC)，无需样品制备。结果表明，在大气压下，氩气流中具有不同电离势和质子亲和力的有机化合物的电离概率微弱地取决于化合物参数，可以为 3.6 10 ^-5 – 1.4 10 ^-4。小鼠和人类生物体液的 VOC 光谱在样品室温下无需样品制备即可获得。证明了使用所提出的方法诊断病理变化的可能性。