Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry was introduced over 30 years ago, and it now plays a key role in several areas, including the characterization of microorganisms and tissue imaging. Lasers are, of course, a central component in MALDI mass spectrometers, but in commercial systems, the type of laser is determined by the instrument manufacturer, and for the operator, their only practical consideration is the selection of the optimal laser power, or fluence, that gives them the best quality spectrum for a given sample and matrix combination.

中文翻译：

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用于基质辅助激光解吸电离的激光器

基质辅助激光解吸/电离 (MALDI) 质谱法于 30 多年前推出，现在它在多个领域发挥着关键作用，包括微生物表征和组织成像。激光器当然是 MALDI 质谱仪的核心组件，但在商业系统中，激光器的类型由仪器制造商决定，对于操作员来说，他们唯一实际考虑的是选择最佳的激光功率或能量密度，这为给定的样品和基质组合提供了最佳质量的光谱。