Abstract

The antibacterial properties of chitosan and self-repairing properties of collagen-I play important roles in the medical field. New types of collagen-I/chitosan/methyl vinyl silicone rubber materials have been synthesized by blending and grafting copolymerization. The effects of chitosan contents on mechanical and antibacterial properties of collagen-I/chitosan/methyl vinyl silicone rubber were investigated, while the morphology and molecular structure were observed and analyzed. It was determined that the antibacterial and self-repairing properties of collagen-I/chitosan/methyl vinyl silicone rubber were better than those of methyl vinyl silicone rubber. Additionally, the optimal contents of chitosan and collagen-I were determined to be 5 wt % and 5 mg/mL, respectively.

中文翻译：

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壳聚糖/甲基乙烯基硅橡胶上I型胶原接枝的影响因素

摘要

壳聚糖的抗菌特性和I型胶原蛋白的自我修复特性在医学领域发挥着重要作用。通过共混和接枝共聚合成了新型胶原-I/壳聚糖/甲基乙烯基硅橡胶材料。研究了壳聚糖含量对I型胶原/壳聚糖/甲基乙烯基硅橡胶力学性能和抗菌性能的影响，同时观察和分析了其形貌和分子结构。确定胶原-I/壳聚糖/甲基乙烯基硅橡胶的抗菌和自修复性能优于甲基乙烯基硅橡胶。此外，壳聚糖和胶原蛋白-I 的最佳含量分别确定为 5 wt% 和 5 mg/mL。