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Frequency distribution of space groups in soluble and membrane proteins and their complexes
Acta Crystallographica Section F ( IF 1.072 ) Pub Date : 2021-06-07 , DOI: 10.1107/s2053230x21005719
Rajneesh K Gaur 1
Affiliation  

The space-group frequency distributions for two types of proteins and their complexes are explored. Based on the incremental availability of data in the Protein Data Bank, an analytical assessment shows a preferential distribution of three space groups, i.e.P212121 > P1211 > C121, in soluble and membrane proteins as well as in their complexes. In membrane proteins, the order of the three space groups is P212121 > C121 > P1211. The distribution of these space groups also shows the same pattern whether a protein crystallizes with a monomer or an oligomer in the asymmetric unit. The results also indicate that the sizes of the two entities in the structures of soluble proteins crystallized as complexes do not influence the frequency distribution of space groups. In general, it can be concluded that the space-group frequency distribution is homogenous across different types of proteins and their complexes.

中文翻译:

可溶性和膜蛋白及其复合物中空间群的频率分布

探索了两种类型的蛋白质及其复合物的空间群频率分布。根据蛋白质数据库中数据增量可用性分析评估显示可溶性和膜蛋白以及在他们的复合体中。在膜蛋白中,三个空间群的顺序是P 2 1 2 1 2 1 > C 121 > P 12 1 1。无论蛋白质以单体还是寡聚体结晶,这些空间群的分布也显示出相同的模式。不对称单位。结果还表明,结晶为复合物的可溶性蛋白质结构中两个实体的大小不影响空间群的频率分布。一般来说,可以得出结论,不同类型的蛋白质及其复合物的空间群频率分布是均匀的。
更新日期:2021-06-08
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