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Fabrication of microstructured planar chromatography platforms via laser ablation
Journal of Liquid Chromatography & Related Technologies ( IF 1.3 ) Pub Date : 2021-06-06 , DOI: 10.1080/10826076.2021.1933025
Ronán McCann 1, 2, 3, 4 , Mercedes Vázquez 1, 2, 3, 5 , Apryll Stalcup 3, 5 , Dermot Brabazon 1, 2, 3, 4
Affiliation  

Abstract

The field of planar chromatography has seen a resurgence due to interest in novel fabrication techniques for sorbent (stationary phase) layers. These novel sorbents must have high surface areas and achieve separations over short distances. Here, we present the first attempt to fabricate a planar chromatographic platform via laser ablation. Microchannels of 24 µm × 68 µm depth were produced using an Nd:YAG laser on cyclic olefin polymer substrates which act as the stationary phase. These plates were then applied to a proof-of-concept organic dye separation and were able to resolve a binary dye mixture over 11 mm of plate length. Results showed promising potential for laser ablation as a new fabrication technique for planar chromatographic substrates.



中文翻译:

通过激光烧蚀制造微结构平面色谱平台

摘要

由于对吸附剂(固定相)层的新型制造技术的兴趣,平面色谱领域已经复苏。这些新型吸附剂必须具有高表面积并在短距离内实现分离。在这里,我们首次尝试通过激光烧蚀制造平面色谱平台。使用 Nd:YAG 激光在作为固定相的环烯烃聚合物基材上产生 24 µm × 68 µm 深度的微通道。然后将这些板应用于概念验证有机染料分离,并能够分离超过 11 毫米板长度的二元染料混合物。结果表明,激光烧蚀作为一种新的平面色谱基底制造技术具有巨大的潜力。

更新日期:2021-06-06
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