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Nanocomposites based on biocompatible polymers and graphene oxide for antibacterial coatings
Polymers and Polymer Composites ( IF 2.1 ) Pub Date : 2021-06-07 , DOI: 10.1177/09673911211020601
Fika Fauzi 1 , Muhammad Miqdam Musawwa 2 , Habibi Hidayat 2 , Ahmad Kusumaatmaja 3 , Wipsar Sunu Brams Dwandaru 1
Affiliation  

Recently, antibacterial coatings based on graphene oxide (GO) nanocomposites have attracted many studies around the world. The use of polymers as the matrices of GO nanofillers in the nanocomposites has been explored to produce efficient coatings against bacteria. One of the most prospective applications is the incorporation of GO into biocompatible polymers, which can produce antibacterial coatings. Here, recent progresses on the antibacterial coatings of nanocomposites based on biocompatible polymers and GO are reviewed. The effect of GO filler concentrations, biocide materials, and biocompatibility are discussed to find the most efficient antibacterial activity and biocompatibility of nanocomposites. Among biocompatible polymers, chitosan (Cs), poly vinyl alcohol (PVA), and poly lactic acid (PLA) are the most popular matrices used for the nanocomposites. This review also elaborates challenges in the use of other biocompatible polymers. Future works on biocompatible antibacterial coatings should be conducted by considering the concentration of GO nanofillers or adding other materials such as essential oils to suppress the toxicity toward functional cells.



中文翻译:

基于生物相容性聚合物和氧化石墨烯的纳米复合材料用于抗菌涂层

最近,基于氧化石墨烯(GO)纳米复合材料的抗菌涂层吸引了世界各地的许多研究。已经探索了使用聚合物作为纳米复合材料中 GO 纳米填料的基质来生产有效的细菌涂层。最有前景的应用之一是将 GO 掺入生物相容性聚合物中,该聚合物可以生产抗菌涂层。本文综述了基于生物相容性聚合物和 GO 的纳米复合材料抗菌涂层的最新进展。讨论了 GO 填料浓度、杀菌剂材料和生物相容性的影响,以找到纳米复合材料最有效的抗菌活性和生物相容性。在生物相容性聚合物中,壳聚糖 (Cs)、聚乙烯醇 (PVA)、和聚乳酸 (PLA) 是用于纳米复合材料的最流行的基质。本综述还阐述了使用其他生物相容性聚合物的挑战。未来关于生物相容性抗菌涂层的工作应该通过考虑 GO 纳米填料的浓度或添加其他材料(如精油)来抑制对功能细胞的毒性。

更新日期:2021-06-07
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