The purpose of this study was to investigate the effect of sodium butyrate on slaughter performance, serum indexes and the intestinal barrier in rabbits. Six hundred healthy weaned rabbits were randomly divided into three groups (5 replicates per group, 40 rabbits per replicate): control (fed a basal diet), sodium butyrate (fed a basal diet containing 0.5% sodium butyrate) and antibiotic (fed a basal diet containing 0.004% antibiotic). The trial lasted 35 days, including 7 days of pretesting and 28 days of formal testing. The results showed that dietary sodium butyrate supplementation increased the full-bore weight, the half-bore weight and the half-bore rate of rabbits. Meanwhile, the content of aspartate aminotransferase (AST) in serum was increased in rabbits fed the sodium butyrate diet. According to the intestinal barrier, after adding sodium butyrate to feed, the tight junction function of the rabbit intestine is enhanced, and the intestinal microbial composition is also improved. To sum up, after sodium butyrate was added to feed instead of antibiotics, slaughter performance was significantly enhanced, serum indexes were improved, and intestinal barrier function was also enhanced. Therefore, sodium butyrate can be added to feed as an additive and can replace antibiotics.

中文翻译：

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丁酸钠对家兔屠宰性能、血清指标及肠屏障的影响

本研究旨在探讨丁酸钠对家兔屠宰性能、血清指标和肠道屏障的影响。600 只健康断奶兔随机分为三组（每组 5 个重复，每重复 40 只兔子）：对照组（饲喂基础日粮）、丁酸钠（饲喂含有 0.5% 丁酸钠的基础日粮）和抗生素（饲喂基础日粮）。含 0.004% 抗生素的饮食）。试用期为 35 天，包括 7 天的预测试和 28 天的正式测试。结果表明，日粮中添加丁酸钠增加了家兔的全径、半径和半径率。同时，饲喂丁酸钠的家兔血清中天冬氨酸氨基转移酶（AST）的含量增加。根据肠道屏障，饲料中添加丁酸钠后，兔肠道的紧密连接功能增强，肠道微生物组成也得到改善。综上所述，在饲料中添加丁酸钠代替抗生素后，屠宰性能显着提高，血清指标得到改善，肠道屏障功能也得到增强。因此，丁酸钠可以作为添加剂添加到饲料中，可以代替抗生素。