A simple synthesis of new series of functionalized chromene derivatives through an efficient, one-pot, multicomponent reaction of nitroketene N,S-acetals, salicylaldehydes, and cyanoacetohydrazide in ethanol at ambient temperature in good to high yields is reported. This novel efficient method has the advantages of mild reaction conditions, absence of catalyst, simple work-up, and the non-chromatographic purification of products.

中文翻译：

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新型功能化 4H-chromen-4-ylidene 衍生物的一锅法合成

报道了通过硝基烯酮N,S-缩醛、水杨醛和氰基乙酰肼在乙醇中在环境温度下的高效、一锅多组分反应，以良好至高产率简单合成新系列的功能化色烯衍生物。这种新型高效方法具有反应条件温和、无需催化剂、后处理简单、产物无需色谱纯化等优点。