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Brønsted acid catalyzed synthesis of 2-aryl-quinazolinones via cyclization of 2-aminobenzamide with benzonitriles in PEG
Journal of Heterocyclic Chemistry ( IF 2.4 ) Pub Date : 2021-06-05 , DOI: 10.1002/jhet.4321
Sowbhagya Lakshmi Matcha 1 , Bharat Kumar Karasala 2 , Sathish Mohan Botsa 3 , Vidavalur Siddaiah 2
Affiliation  

A simple and efficient Brønsted acid catalyzed synthesis of 2-aryl-quinazolinones via cyclization of 2-aminobenzamides with benzonitrile in PEG under metal and ligand-free condition. All substituted benzonitriles were also well participated with the formation of the corresponding products in moderate to good yields.

中文翻译:

布朗斯台德酸通过 PEG 中 2-氨基苯甲酰胺与苯甲腈的环化反应合成 2-芳基-喹唑啉酮

一种简单有效的布朗斯台德酸催化合成 2-芳基喹唑啉酮,通过 2-氨基苯甲酰胺在 PEG 中在无金属和配体条件下与苄腈环化。所有取代的苯甲腈也很好地参与了相应产物的形成,产率中等至良好。
更新日期:2021-06-05
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