Glutathione transferases are enzymes involved in the detoxification against xenobiotics and noxious compounds. These enzymes catalyse a variety of reactions on many physiological and xenobiotic compounds using glutathione as a co-substrate. Moreover, many compounds are inhibitors of such enzymes. A wide array of biosensors based on glutathione transferases have been developed for analysing a variety of noxious compounds, as well as several biosensors devoted to the detection and quantification of glutathione and of glutathione transferases themselves. Here, we review the state of the art in this active field of research, highlighting the possible applications of such devices.

中文翻译：

---

基于谷胱甘肽转移酶和谷胱甘肽检测的生物传感器概述

谷胱甘肽转移酶是参与对异生物质和有毒化合物进行解毒的酶。这些酶使用谷胱甘肽作为共底物催化许多生理和异生物质化合物的各种反应。此外，许多化合物是此类酶的抑制剂。已经开发了大量基于谷胱甘肽转移酶的生物传感器，用于分析各种有害化合物，以及一些专门用于检测和量化谷胱甘肽和谷胱甘肽转移酶本身的生物传感器。在这里，我们回顾了这一活跃研究领域的最新技术，重点介绍了此类设备的可能应用。