Pelvic exenteration is a highly morbid operation and remains one of the most catastrophic surgical procedures in gynecological oncology. We would like to present the case of total pelvic exenteration for vaginal cancer after radiotherapy for endometrial cancer as a secondary cancer. A 62-year-old woman, whose gravida: 3, parity: 2, body mass index: 35.9 kg/m², presented with complaints of vaginal bleeding. She had undergone a surgery because of a stage IB grade 2 endometrioid-type adenocarcinoma seventeen years previously. Following the surgery, she had external pelvic radiotherapy and brachytherapy. A palpable, solid and ulcerative mass was detected extending from the vaginal cuff area to the vestibulum vagina on the left postero-lateral wall of the vagina. The 5-cm vaginal mass was seen at vaginal examination. A punch biopsy from a pathological examination of the tumoral lesion was reported as a squamous cell carcinoma. Pelvic exenteration was performed and ileo-perineal fistula occurred after six months this surgery. In conclusion, we considered that this malignancy was a secondary malignancy induced by radiotherapy.

中文翻译：

---

阴道癌作为子宫内膜癌和回肠 - 会阴瘘全盆腔切除术后放疗的晚期并发症。

骨盆切除术是一种高度病态的手术，并且仍然是妇科肿瘤学中最具灾难性的外科手术之一。我们想介绍子宫内膜癌放疗后阴道癌全盆腔切除术作为继发性癌症的案例。一名 62 岁女性，妊娠：3，胎次：2，体重指数：35.9 kg/m²，主诉阴道流血。她在 17 年前因 IB 期 2 级子宫内膜样腺癌接受了手术。手术后，她接受了盆腔外放疗和近距离放射治疗。在阴道的左后侧壁上检测到从阴道袖带区域延伸到阴道前庭的可触及、实性和溃疡性肿块。在阴道检查中发现了 5 厘米的阴道肿块。据报道，对肿瘤病变进行病理检查的穿孔活检为鳞状细胞癌。进行了盆腔切除术，手术六个月后发生了回肠 - 会阴瘘。总之，我们认为这种恶性肿瘤是放疗诱发的继发性恶性肿瘤。