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Real-World Data on the Intravascular Microaxial Left Ventricular Flow Pump (Impella) in High-Risk Patients.
Korean Circulation Journal ( IF 2.9 ) Pub Date : 2021-6-5 , DOI: 10.4070/kcj.2021.0102
Sunil V. Rao 1
Affiliation  

Mechanical circulatory support (MCS) devices maintain or improve hemodynamic profiles in patients at risk for hemodynamic deterioration during percutaneous coronary intervention (PCI) or those in cardiogenic shock. Clinical trials of MCS have been difficult to complete due to challenges with equipoise; however, there are several "real-world" comparative effectiveness analyses of outcomes of patients undergoing high-risk PCI or cardiogenic shock with different MCS. This review summarizes the real-world data on Impella and intra-aortic balloon pump, 2 of the most commonly used MCS, and provides insight into the limitations of such data and challenges to completing clinical trials.

中文翻译:

高危患者血管内微轴左心室血流泵 (Impella) 的真实数据。

机械循环支持 (MCS) 设备可维持或改善在经皮冠状动脉介入治疗 (PCI) 或心源性休克期间有血流动力学恶化风险的患者的血流动力学特征。MCS 的临床试验由于平衡的挑战而难以完成;然而,对于不同 MCS 的高危 PCI 或心源性休克患者的结果,有几个“真实世界”的比较有效性分析。本综述总结了 Impella 和主动脉内球囊泵(2 种最常用的 MCS)的真实数据,并提供了对此类数据的局限性和完成临床试验的挑战的见解。
更新日期:2021-06-06
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