For mobile lung tumors, four-dimensional computer tomography (4D CT) is often used for simulation and treatment planning. Localization accuracy remains a challenge in lung stereotactic body radiation therapy (SBRT) treatments. An attractive image guidance method to increase localization accuracy is 4D cone-beam CT (CBCT) as it allows for visualization of tumor motion with reduced motion artifacts. However, acquisition and reconstruction of 4D CBCT differ from that of 4D CT. This study evaluates the discrepancies between the reconstructed motion of 4D CBCT and 4D CT imaging over a wide range of sine target motion parameters and patient waveforms.

中文翻译：

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四维计算机断层扫描与四维锥束计算机断层扫描对移动目标轨迹的评价

对于移动性肺肿瘤，通常使用四维计算机断层扫描（4D CT）进行模拟和治疗计划。定位准确性仍然是肺立体定向放射治疗 (SBRT) 治疗中的一个挑战。一种提高定位精度的有吸引力的图像引导方法是 4D 锥束 CT (CBCT)，因为它允许可视化肿瘤运动并减少运动伪影。然而，4D CBCT 的采集和重建与 4D CT 不同。本研究评估了 4D CBCT 和 4D CT 成像在各种正弦目标运动参数和患者波形上的重建运动之间的差异。