A high morning surge in systolic blood pressure poses a risk in people who have cardiovascular disease. We investigated the relationship between this phenomenon and the SYNTAX score I in patients who had stable coronary artery disease.

Our single-center study included 125 consecutive patients (109 men and 16 women; mean age, 54.3 ± 9 yr) in whom coronary angiography revealed stable coronary artery disease. We calculated each patient's sleep-trough morning surge in systolic blood pressure, then calculated the SYNTAX score I.

The morning surge was significantly higher in patients whose score was >22 (mean, 22.7 ± 13.2) than in those whose score was ≤22 (mean, 12.4 ± 7.5) (P <0.001). Forward stepwise logistic regression analysis revealed that morning surge in systolic blood pressure was the only independent predictor of an intermediate-to-high score (odds ratio=1.183; 95% CI, 1.025–1.364; P=0.021).

To our knowledge, this is the first study to show an association between morning surge in systolic blood pressure and the SYNTAX score I in patients who have stable coronary artery disease.

收缩压的高早晨激增对患有心血管疾病的人构成风险。我们调查了这种现象与稳定型冠状动脉疾病患者的 SYNTAX 评分 I 之间的关系。

我们的单中心研究包括 125 名连续患者（109 名男性和 16 名女性；平均年龄，54.3 ± 9 岁），其中冠状动脉造影显示稳定的冠状动脉疾病。我们计算了每位患者的睡眠低谷早晨收缩压峰值，然后计算了 SYNTAX 评分 I。

评分>22（平均，22.7±13.2）的患者晨峰显着高于评分≤22（平均，12.4±7.5）的患者（P <0.001）。正向逐步逻辑回归分析显示，早晨收缩压升高是中高分的唯一独立预测因素（比值比 = 1.183；95% CI，1.025–1.364；P = 0.021）。

据我们所知，这是第一项显示在患有稳定型冠状动脉疾病的患者中早晨收缩压升高与 SYNTAX I 评分之间存在关联的研究。