The recent Kidney Disease: Improving Global Outcomes (KDIGO) consensus conference proposed a universal nomenclature calling for “Kidney Disease” (KD) to be applied to every form of kidney dysfunction, regardless of etiology. We recognize that the estimated glomerular filtration rate and urine albumin:creatinine ratio are limited in their application to the broad spectrum of KD. However, there are additional in vitro and advanced diagnostic options that can help identify the underlying cause of KD and inform about prognosis and management. While the overarching benefit of generalizing KD as a medical problem lies with screening and detection, the downsides attributable to a nonexact diagnosis (i.e., unclear prognosis and management strategy) are considerable. Finally, the terms “acute kidney injury” and “worsening renal function” are currently used interchangeably by nephrologists and cardiologists alike, and a universal adoption of one term will likely be a sizeable challenge. To be of greater benefit, we propose KD be used as a starting point and that the etiology and other epigenetic determinants of illness continue to be evaluated and characterized.
Cardiorenal Med

中文翻译：

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来自 KDIGO 的肾功能命名法：术语过度简化的缺点

最近的肾脏疾病：改善全球结果 (KDIGO) 共识会议提出了一种通用命名法，呼吁将“肾脏疾病”(KD) 应用于各种形式的肾功能障碍，无论其病因如何。我们认识到，估计的肾小球滤过率和尿白蛋白：肌酐比值在其对广谱 KD 的应用方面受到限制。然而，还有其他体外和高级诊断选项可以帮助确定 KD 的根本原因并告知预后和管理。虽然将 KD 概括为医学问题的首要好处在于筛查和检测，但归因于不准确诊断（即，不明确的预后和管理策略）的缺点是相当大的。最后，“急性肾损伤”和“肾功能恶化”这两个术语目前被肾脏病学家和心脏病学家互换使用，普遍采用一个术语可能是一个巨大的挑战。为了获得更大的益处，我们建议将 KD 作为起点，并继续评估和表征疾病的病因和其他表观遗传决定因素。
心肾医学