One of the suggested ways of the use of nanoparticles in virology implies their association with and subsequent deactivation of virions. The conditions determining the efficiency of this approach in vivo are now not clear. Herein, I propose the first kinetic model describing the corresponding processes and clarifying these conditions. My analysis indicates that nanoparticles can decrease concentration of infected cells by a factor of one order of magnitude, but this decrease itself (without feedback of the immune system) is insufficient for full eradication of infection. It can, however, induce delay in the progress of infection, and this delay can help to form sufficient feedback of the immune system.

在病毒学中使用纳米粒子的建议方法之一暗示它们与病毒粒子的关联和随后的灭活。决定这种方法在体内的效率的条件现在还不清楚。在此，我提出了描述相应过程并阐明这些条件的第一个动力学模型。我的分析表明，纳米粒子可以将受感染细胞的浓度降低一个数量级，但这种降低本身（没有免疫系统的反馈）不足以完全根除感染。然而，它可以导致感染进程的延迟，而这种延迟可以帮助免疫系统形成足够的反馈。