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Can altered colostrum miRNA expression profile after cesarean delivery be a risk factor for autoimmune diseases?
American Journal of Reproductive Immunology ( IF 3.6 ) Pub Date : 2021-06-03 , DOI: 10.1111/aji.13472
Fatma Humeyra Yerlikaya 1 , Duygu Eryavuz Onmaz 1 , Huseyin Altunhan 2 , Merve Ilhan 3
Affiliation  

The cesarean section (CS) rate has increased significantly in North America, Western Europe, and Latin America. However, it has been reported that the incidence of inflammatory and autoimmune diseases such as asthma and type 1 diabetes increased in parallel with CS in these countries. Our aim was to investigate the expression level of miRNAs associated with inflammatory response and autoimmune diseases in colostrum samples and contribute to elucidating the role of CS in the pathogenesis of immune system–related diseases.

中文翻译:

剖宫产后初乳 miRNA 表达谱的改变是否会成为自身免疫性疾病的危险因素?

北美、西欧和拉丁美洲的剖宫产率(CS)显着增加。然而,据报道,在这些国家,哮喘和 1 型糖尿病等炎症和自身免疫性疾病的发病率与 CS 同步增加。我们的目的是研究初乳样品中与炎症反应和自身免疫性疾病相关的 miRNA 的表达水平,并有助于阐明 CS 在免疫系统相关疾病发病机制中的作用。
更新日期:2021-06-03
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