A new denudatine-type C20-diterpenoid alkaloid bearing a rare C-15 ketone carbonyl and 16,17-epoxy group, named arcutisine (1), together with 24 known compounds (2-25), were obtained from the roots of Aconitum fischeri var. arcuatum. Their structures were established by various spectroscopic analyses. Among them, compounds 1 and 2 were both isolated from a natural source for the first time. Besides, compounds 7 and 10 showed weak effect on anti-inflammatory activity with the inhibition rate of 33.5% and 33.7% at the concentration of 40 µM.

中文翻译：

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一种新的 Denudatin C 型

从乌头的根中获得了一种新的带有稀有C-15酮羰基和16,17-环氧基团的地努他汀型C 20 -二萜生物碱，命名为arcutisine ( 1 )，以及24种已知化合物( 2 - 25 )。费舍里变种 弓形体。它们的结构是通过各种光谱分析确定的。其中，化合物1和2均为首次从天然来源中分离得到。此外，化合物7和10对抗炎活性的影响较弱，在40 μ M的浓度下抑制率为33.5%和33.7%  。