Experimental evidence demonstrated a crucial role of TROAP (Trophinin-associated protein) in regulating the cell proliferation of multiple tumors, while TROAP expression and function were largely unknown in glioma. We aimed to investigate the oncogenic role of TROAP and its potential mechanisms in gliomagenesis.

中文翻译：

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TROAP在胶质瘤细胞中通过Wnt/β-Catenin信号通路调控细胞周期并促进肿瘤进展

实验证据表明 TROAP（肌钙蛋白相关蛋白）在调节多种肿瘤的细胞增殖中起关键作用，而 TROAP 表达和功能在胶质瘤中很大程度上未知。我们旨在研究 TROAP 的致癌作用及其在胶质瘤发生中的潜在机制。