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Increased epithelial galectin-13 expression associates with eosinophilic airway inflammation in asthma
Clinical & Experimental Allergy ( IF 6.1 ) Pub Date : 2021-06-02 , DOI: 10.1111/cea.13961
Lingling Yi 1, 2 , Shuchen Zhang 3 , Yuchen Feng 1, 2 , Wenliang Wu 1, 2 , Chenli Chang 1, 2 , Dian Chen 1, 2 , Shengchong Chen 1, 2 , Jianping Zhao 1, 2 , Guohua Zhen 1, 2
Affiliation  

Airway eosinophilic inflammation is a central feature in asthma which is mainly driven by type 2 response. The expression of galectin-13 was up-regulated in a parasitic infection model which is also characterized by type 2 immune response. We hypothesized that galectin-13 may be involved in airway eosinophilic inflammation in asthma.

中文翻译:

上皮 galectin-13 表达增加与哮喘中的嗜酸性气道炎症相关

气道嗜酸性炎症是哮喘的核心特征,主要由 2 型反应驱动。在寄生虫感染模型中,galectin-13 的表达上调,该模型也以 2 型免疫反应为特征。我们假设 galectin-13 可能与哮喘的气道嗜酸性粒细胞炎症有关。
更新日期:2021-06-02
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