A distributed lumped parameter (DLP) model of blood flow was recently developed that can be simulated in minutes while still incorporating complex sources of energy dissipation in blood vessels. The aim of this work was to extend the previous DLP modeling framework to include fluid–structure interactions (DLP-FSI). This was done by using a simple compliance term to calculate pressure that does not increase the simulation complexity of the original DLP models. Verification and validation studies found DLP-FSI simulations had good agreement compared to analytical solutions of the wave equations, experimental measurements of pulsatile flow in elastic tubes, and in vivo MRI measurements of thoracic aortic flow. This new development of DLP-FSI allows for significantly improved computational efficiency of FSI simulations compared to FSI approaches that solve the full 3D conservation of mass and momentum equations while also including the complex sources of energy dissipation occurring in cardiovascular flows that other simplified models neglect.

最近开发了一种血流的分布式集总参数 (DLP) 模型，该模型可以在几分钟内进行模拟，同时仍然在血管中包含复杂的能量耗散源。这项工作的目的是扩展以前的 DLP 建模框架，以包括流固耦合 (DLP-FSI)。这是通过使用一个简单的合规项来计算压力来完成的，该压力不会增加原始 DLP 模型的模拟复杂性。验证和验证研究发现，与波动方程的解析解、弹性管中脉动流的实验测量以及胸主动脉血流的体内 MRI 测量相比，DLP-FSI 模拟具有良好的一致性。