Allodynia, the clinical marker of central sensitization, affects even simple daily living activities and increases the tendency for migraine to be more resistant to treatment and have a chronic course. Migraine that impairs quality of life can often be treated with variable pharmaceutical agents, but with various side effects. Transcranial direct current stimulation (tDCS) is a potential alternative treatment for migraine prophylaxis.

中文翻译：

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异常性疼痛是经颅直流电刺激预防偏头痛有效性的决定因素吗？

异常性疼痛是中枢敏化的临床标志物，它甚至会影响简单的日常生活活动，并增加偏头痛对治疗更具抵抗力并具有慢性病程的趋势。损害生活质量的偏头痛通常可以用不同的药物治疗，但会产生各种副作用。经颅直流电刺激 (tDCS) 是一种潜在的偏头痛预防替代疗法。