Abstract

The aim of this study was to investigate the serum and meat metabolomic changes according to the genetic potential for muscularity of non-castrated Nellore males and its association with phenotypic traits. Forty-eight non-castrated Nellore males were separated into two groups based on their genetic potential for post-weaning muscularity: high (HM) and low (LM). Selection for muscularity did not cause noticeable differences in the traits evaluated during the finishing phase and after slaughter. However, several metabolites in meat and serum, have changed according to the muscularity group. HM animals presented an over-abundance of glycerol, glutamine, choline, methylhistidine, betaine, creatinine and methionine in serum, compared with their LM counterparts. Similarly, the meat samples of HM animals were rich in glucose-6-phosphate, lactate, pyruvate, creatinine, betaine, choline, glycerol and arginine relative to LM bulls. Inosine monophosphate was the only metabolite over-abundant in LM animals. In conclusion, the genetic potential for post-weaning muscularity did not affect performance during the finishing phase, carcass traits and meat quality. However, multivariate analysis shows that the genetic potential of muscularity can be correlated with serum lipid and protein metabolites, and with energy metabolism in meat, providing a footprint of cattle muscularity metabolism.

摘要

本研究的目的是根据未阉割的 Nellore 雄性肌肉的遗传潜力及其与表型性状的关联，研究血清和肉代谢组学变化。48 头未阉割的 Nellore 公牛根据断奶后肌肉发达的遗传潜力分为两组：高 (HM) 和低 (LM)。肌肉发达的选择不会导致肥育阶段和屠宰后评估的性状发生明显差异。然而，肉和血清中的几种代谢物根据肌肉群发生了变化。与其 LM 对应物相比，HM 动物在血清中呈现出过量的甘油、谷氨酰胺、胆碱、甲基组氨酸、甜菜碱、肌酸酐和甲硫氨酸。同样，HM 动物的肉样品富含 6-磷酸葡萄糖、乳酸、丙酮酸、肌酸酐、甜菜碱、胆碱、甘油和精氨酸相对于 LM 公牛。肌苷一磷酸是 LM 动物中唯一过量的代谢物。总之，断奶后肌肉发达的遗传潜力不影响肥育阶段的性能、胴体性状和肉质。然而，多变量分析表明，肌肉发达的遗传潜力可能与血清脂质和蛋白质代谢物以及肉类中的能量代谢相关，从而提供了牛肌肉发达代谢的足迹。