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Determination of scalp hair selenium concentrations in Algerian psoriatic individuals using k0-standardization based on neutron activation analysis method
Radiochimica Acta ( IF 1.8 ) Pub Date : 2021-06-01 , DOI: 10.1515/ract-2020-0090
Ammar Mansouri 1 , Lylia Hamidatou Alghem 2 , Oum El-Kheir Mokhtari 3 , Mohammed El-Amine Benamar 4
Affiliation  

Psoriasis is a dermatological disease that affects 2–3% of the Algerian population. Selenium has a positive impact on psoriasis. Selenium plays an important role in protecting free radical damage as a component of the glutathione peroxidase enzyme. The objective of this investigation was to assess the status of selenium in the hair of Algerian patients suffering from psoriasis. Fifty-eight scalp hair samples were collected from Algerian patients with psoriasis, classified by gender and four age groups: 36 females and 22 males, aged between 9 and 79 years. Thirty healthy subjects aged 9–74 years were also surveyed for control purposes. Selenium content was measured for all scalp hair samples using the k 0 -standardization of neutron activation analysis. The average selenium concentration for controls and patients were 0.39 ± 0.18 and 0.28 ± 0.13 μg/g respectively. Selenium concentration for female and male controls and patients, were 0.35 ± 0.17, 0.47 ± 0.19, 0.28 ± 0.14, and 0.28 ± 0.11 μg/g, respectively. There is a significant difference ( p < 0.05) between selenium level in patients and in controls. Selenium concentrations in psoriatics’ scalp hair can be affected by both gender and age. Measured selenium contents have been approved by the quality assurance and quality control procedure (QA/QC).

中文翻译:

使用基于中子活化分析方法的 k0 标准化测定阿尔及利亚银屑病患者的头皮头发硒浓度

银屑病是一种皮肤病,影响 2-3% 的阿尔及利亚人口。硒对银屑病有积极影响。硒作为谷胱甘肽过氧化物酶的组成部分,在保护自由基损伤方面发挥着重要作用。本次调查的目的是评估阿尔及利亚银屑病患者头发中硒的状况。从阿尔及利亚银屑病患者中收集了 58 份头皮毛发样本,按性别和四个年龄组分类:36 名女性和 22 名男性,年龄在 9 至 79 岁之间。为了控制目的,还对 30 名 9-74 岁的健康受试者进行了调查。使用中子活化分析的 k 0 标准化测量所有头皮毛发样品的硒含量。对照和患者的平均硒浓度为0.39±0.18和0.28±0。分别为 13 μg/g。女性和男性对照和患者的硒浓度分别为 0.35 ± 0.17、0.47 ± 0.19、0.28 ± 0.14 和 0.28 ± 0.11 μg/g。患者和对照组中硒水平之间存在显着差异(p <0.05)。银屑病患者头皮中的硒浓度会受到性别和年龄的影响。测得的硒含量已通过质量保证和质量控制程序 (QA/QC) 的批准。
更新日期:2021-05-28
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