Theft of prescription drugs is nothing new for Canadian pharmacists. Recently, an increasing body of literature has covered the diversion of controlled substances from Canadian hospitals. However, little has been published in the scientific literature concerning the data collected by Health Canada’s Loss or Theft Report Program regulated under the Controlled Drugs and Substances Act. Data from January 1, 2014, to December 31, 2018, were obtained from Health Canada’s Office of Controlled Substances (OCS). Reports to the OCS are mostly provided by pharmacies and hospitals, by veterinarian, dental, and physician clinics, pharmaceutical distributors and producers, and federal establishments and organizations. Entries include information related to the date, province, and location type; type of loss or theft; and generic name of the product, its strength, dosage form, quantity, and drug identification number. During the studied period, 45,379 submissions to the OCS provided information to create 213,895 entries to the database. After exclusions, 212,317 reports were retained for analysis. Opioids count for 45% of reports, benzodiazepines for 29%, and psychostimulants for 21%. Approximately, 29 million individual doses were lost or stolen of which 7.7 million were opioids (26%), totalizing approximately 178 million oral morphine milligram equivalents with 95% having been lost or stolen in community pharmacies. Moreover, approximately four out of 10 individual doses lost in community pharmacies are unexplained losses, which represent about 4.6 million individual doses. Reporting lost or stolen controlled substances and precursors is essential to tracking the diversion of Canada’s prescription drugs. Pharmacists therefore have an important role to play when it comes to minimizing their potential diversion. A better understanding of the situation across Canada may help to increase health care professionals’ awareness, improve practices, enhance the quality of collected data, and prevent further losses and thefts.

对于加拿大药剂师而言，盗窃处方药并不是什么新鲜事。最近，越来越多的文献报道了从加拿大医院转移管制药物的情况。但是，有关由加拿大卫生部《受管制药物和物质法》管制的“失窃或失窃报告程序”收集的数据的科学文献很少发表。2014年1月1日至2018年12月31日的数据来自加拿大卫生部受控物质办公室（OCS）。向OCS的报告主要由药房和医院，兽医，牙科和医师诊所，药品分销商和生产商以及联邦机构和组织提供。条目包括与日期，省和位置类型有关的信息；丢失或盗窃的类型；产品的通用名称，其强度，剂型，数量和药物识别号。在研究期间，向OCS提交了45,379条信息，提供了创建213,895条数据库条目的信息。排除后，保留了212,317份报告进行分析。阿片类药物占报告的45％，苯二氮卓类药物占29％，精神兴奋剂占21％。大约有2900万单剂丢失或被盗，其中770万是阿片类药物（占26％），总计约1.78亿口服吗啡毫克当量，其中95％在社区药房丢失或被盗。此外，在社区药房中损失的十分之四的个体剂量是无法解释的损失，约占460万个体剂量。报告丢失或失窃的管制药物和前体对于追踪加拿大处方药的转移至关重要。因此，在使他们的潜在转移最小化方面，药剂师可以发挥重要作用。更好地了解加拿大各地的情况可能有助于提高医疗保健专业人员的意识，改进做法，提高收集数据的质量并防止进一步的损失和盗窃。