The differential diagnosis for an acute Crohn’s flare should include enteric infection, a challenging yet critical distinction to make when determining appropriate therapy. Since both present similarly, identification of an enteric infection should be performed with comprehensive stool microbial testing. In the setting of moderate-to-severe disease, patients on biologic therapy may be more prone to infectious complications. We present a patient with chronic Crohn’s disease with an unusual, previously undetected enteric infection due to Plesiomonas shigelloides. Once identified, appropriate antibiotic treatment led to resolution of the patient’s acute symptomatology. This is the first reported case of P. shigelloides infection in Crohn’s disease.
Case Rep Gastroenterol 2021;15:475–477

中文翻译：

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克罗恩病叠加感染性结肠炎

急性克罗恩病的鉴别诊断应包括肠道感染，这是在确定适当治疗时做出的具有挑战性但至关重要的区别。由于两者存在相似性，因此应通过综合粪便微生物检测来确定肠道感染。在中度至重度疾病的情况下，接受生物治疗的患者可能更容易出现感染并发症。我们介绍了一名患有慢性克罗恩病的患者，该患者患有异常的、以前未被发现的由志贺单胞菌引起的肠道感染。一旦确定，适当的抗生素治疗可以解决患者的急性症状。这是克罗恩病中第一个报道的志贺氏菌感染病例。
Case Rep Gastroenterol 2021；15:475–477