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Which patients benefit from preoperative biliary drainage in resectable pancreatic cancer?
Expert Review of Gastroenterology & Hepatology ( IF 3.9 ) Pub Date : 2021-05-26 , DOI: 10.1080/17474124.2021.1915127
Sarah Blacker 1 , Rajiv P Lahiri 1 , Mary Phillips 2 , Graham Pinn 1 , Tim D Pencavel 1 , Rajesh Kumar 1 , Angela T Riga 1 , Tim R Worthington 1 , Nariman D Karanjia 1 , Adam E Frampton 1, 3
Affiliation  

ABSTRACT

Recent studies have indicated that preoperative biliary drainage (PBD) should not be routinely performed in all patients suffering from obstructive jaundice before pancreatic surgery. The severity of jaundice that mandates PBD has yet to be defined. The evaluated paper examines the impact of PBD on intra-operative, and post-operative outcomes in patients initially presenting with severe obstructive jaundice (bilirubin ≥250 μmol/L). In this key paper evaluation, the impact of PBD versus a direct surgery (DS) approach is discussed. The arguments for and against each approach are considered with regards to drainage associated morbidity and mortality, resection rates, survival and the impact of chemotherapy and malnutrition. Concentrating on resectable head of pancreas tumors, this mini-review aims to scrutinize the authors’ recommendations, alongside those of prominent papers in the field.



中文翻译:

哪些患者可从可切除胰腺癌的术前胆汁引流中获益?

摘要

最近的研究表明,对于所有患有梗阻性黄疸的患者,在胰腺手术前不应常规进行术前胆道引流 (PBD)。需要进行 PBD 的黄疸严重程度尚未确定。评估论文检查了 PBD 对最初出现严重阻塞性黄疸(胆红素 ≥ 250 μmol/L)患者术中和术后结果的影响。在这篇重要的论文评估中,讨论了 PBD 与直接手术 (DS) 方法的影响。支持和反对每种方法的论据都考虑了引流相关的发病率和死亡率、切除率、存活率以及化疗和营养不良的影响。专注于可切除的胰头肿瘤,这篇小型综述旨在仔细审查作者的建议,

更新日期:2021-05-26
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