Successful containment of a flight-imported COVID-19 outbreak through extensive contact tracing, systematic testing and mandatory quarantine: Lessons from Vietnam,Travel Medicine and Infectious Disease

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Successful containment of a flight-imported COVID-19 outbreak through extensive contact tracing, systematic testing and mandatory quarantine: Lessons from Vietnam
Travel Medicine and Infectious Disease ( IF 12.0 ) Pub Date : 2021-05-26 , DOI: 10.1016/j.tmaid.2021.102084
Ha-Linh Quach ₁ , Ngoc-Anh Thi Hoang ₁ , Cong Khanh Nguyen ₂ , Quang Thai Pham ₃ , Cong Dinh Phung ₄ , Nhu Duong Tran ₅ , Quynh Mai Thi Le ₅ , Duy Nghia Ngu ₂ , Anh Tu Tran ₂ , Ngoc Quang La ₆ , Dai Quang Tran ₇ , Trong Tai Nguyen ₈ , Florian Vogt ₉ , Duc Anh Dang ₅

Affiliation

Department of Communicable Diseases Control, National Institute of Hygiene and Epidemiology, Hanoi, Viet Nam; National Centre for Epidemiology and Population Health, Research School of Population Health, College of Health and Medicine, Australian National University, Canberra, Australia.
Department of Communicable Diseases Control, National Institute of Hygiene and Epidemiology, Hanoi, Viet Nam.
Department of Communicable Diseases Control, National Institute of Hygiene and Epidemiology, Hanoi, Viet Nam; Institute of Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Viet Nam.
National Agency for Science and Technology Information, Ministry of Science and Technology, Hanoi, Viet Nam.
National Institute of Hygiene and Epidemiology, Hanoi, Viet Nam.
Ha Noi University of Public Health, Hanoi, Viet Nam.
General Department of Preventive Medicine, Ministry of Health, Hanoi, Viet Nam.
Institute of Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Viet Nam.
National Centre for Epidemiology and Population Health, Research School of Population Health, College of Health and Medicine, Australian National University, Canberra, Australia; The Kirby Institute, University of New South Wales, Sydney, NSW, Australia.

Background

The importation of SARS-CoV-2 through air travel poses substantial risks to generate new COVID-19 outbreaks. Timely contact tracing is particularly crucial to limit onwards transmission in settings without established community transmission.

Methods

We conducted an in-depth analysis of the response to a big flight-associated COVID-19 outbreak in Vietnam in March 2020 that involved contact tracing, systematic testing and strict quarantine up to third generation contacts.

Results

183 primary contacts from the flight as well as 1000 secondary and 311 third generation contacts were traced, tested, and quarantined across 15 provinces across Vietnam. The protracted confirmation of the index case at 3 days and 19 h after arrival resulted in isolation/quarantine delays of 6.8 days (IQR 6.3–6.8) and 5.8 days (IQR 5.8–7.0) for primary and secondary cases, respectively, which generated 84.0 and 26.4 person-days of community exposure from primary and secondary cases, respectively. Nevertheless, only 5 secondary cases occurred.

Conclusions

A large flight-related COVID-19 cluster was successfully contained through timely, systematic and comprehensive public health responses despite delayed index case identification. Multiagency collaboration and pre-established mechanisms are crucial for low and middle income countries like Vietnam to limit community transmission after COVID-19 importation through air travel.

中文翻译：

通过广泛的接触者追踪、系统测试和强制隔离成功遏制航班输入的 COVID-19 爆发：来自越南的经验教训

背景

通过航空旅行输入 SARS-CoV-2 会带来引发新的 COVID-19 疫情的巨大风险。及时追踪接触者对于限制在尚未建立社区传播的环境中继续传播尤为重要。

方法

我们对 2020 年 3 月在越南发生的与飞行相关的 COVID-19 大爆发的应对措施进行了深入分析，其中涉及接触者追踪、系统测试和对第三代接触者的严格隔离。

结果

该航班的 183 名主要接触者以及 1000 名第二代和 311 名第三代接触者在越南 15 个省进行了追踪、检测和隔离。在抵达后 3 天和 19 小时对指示病例的长期确认导致原发病例和继发病例的隔离/隔离延迟分别为 6.8 天（IQR 6.3-6.8）和 5.8 天（IQR 5.8-7.0），产生 84.0初级和次级病例的社区暴露分别为 26.4 人日。然而，仅发生了 5 例继发病例。