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A Novel Lactam Metabolite from Penicillium sclerotium D35
Chemistry of Natural Compounds ( IF 0.8 ) Pub Date : 2021-05-26 , DOI: 10.1007/s10600-021-03378-y
T. Liu , C. L. Gong , J. Zhao , D. Dan , T. T. Zhang , L. L. Gao , Q. Zhang

A novel lactam metabolite, 1-pentyl-8-oxa-3,6-diazabicyclo[3.2.1]octane-2,4,7-trione (1), was isolated from Penicillium sclerotium D35. The structure of the new compound 1 was elucidated by spectroscopic methods, including 1D and 2D NMR data and HR-MS. Compound 1 showed moderate nematode suppression activity with LC50 values of 344.722 mg/L.



中文翻译:

青霉菌D35的新型内酰胺代谢产物

青霉菌D35中分离出一种新型内酰胺代谢物1-戊基-8-氧杂-3,6-二氮杂双环[3.2.1]辛烷-2,4,7-三酮(1)。通过光谱方法阐明了新化合物1的结构,包括1D和2D NMR数据以及HR-MS。化合物1表现出中等的线虫抑制活性,LC 50值为344.722 mg / L。

更新日期:2021-05-26
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