Molecular nanoparticles, MNPs, characterized by well-defined chemical formulas, structures, and sizes can interact with a variety of proteins. Fullerenes, carboranes, and gold nanoclusters well represent the diversity of MNPs properties available in nanoscience. They can have diameters smaller than 1.5 nm, be hydrophilic or hydrophobic, and can use a paraphernalia of means to establish local and global interactions with the amino acidic residues of proteins. Proteins, endowed as they are with an assortment of pockets, crevices, and gaps are natural supramolecular hosts to incorporate/hide/transport MNPs directly in water with a facile and “green” approach.

中文翻译：

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在蛋白质中掺入分子纳米颗粒：治疗诊断学中的特洛伊木马方法

以明确定义的化学式、结构和尺寸为特征的分子纳米粒子 MNP 可以与多种蛋白质相互作用。富勒烯、碳硼烷和金纳米团簇很好地代表了纳米科学中可用的 MNP 特性的多样性。它们可以具有小于 1.5 nm 的直径，可以是亲水的或疏水的，并且可以使用各种手段来建立与蛋白质氨基酸残基的局部和全局相互作用。具有各种口袋、裂缝和间隙的蛋白质是天然的超分子宿主，可以通过简便和“绿色”的方法直接在水中掺入/隐藏/运输 MNP。