Clinical Psychological Science ( IF 4.8 ) Pub Date : 2021-05-25 , DOI: 10.1177/21677026211009508 Giuseppe Salvo 1 , Samantha Provenzano 2 , Maria Di Bello 3 , Francesca D’Olimpio 4 , Cristina Ottaviani 3, 5 , Francesco Mancini 1, 2
The study was designed to test the hypothesis that indirect inhibition of the insula via cathodal transcranial direct current stimulation (tDCS) would decrease disgust and moral rigidity in 36 healthy individuals undergoing 15 min of tDCS over the temporal lobe. To obtain a comprehensive assessment of disgust, we used subjective (affect rating), physiological (heart rate variability [HRV]), and implicit measures (word-fragment completion), and moral judgment was assessed by asking participants to rate the deontological and altruistic moral wrongness of a revised version of the moral foundations vignettes. We found anodal and cathodal stimulations to, respectively, enhance and decrease self-reported disgust, deontological morality, and HRV. Note that these effects were stronger in individuals with higher levels of obsessive compulsive (OC) traits. Because disgust and sensitivity to deontological guilt are among the most impairing features in OC disorder, it is auspicious that cathodal tDCS could be implemented to reduce such symptoms.
中文翻译:
不道德的肮脏:通过无创性脑刺激操纵厌恶和道德僵硬,作为强迫症的有希望的治疗工具
这项研究旨在检验以下假设:通过阴极经颅直流电刺激(tDCS)间接抑制绝缘岛将减少36名在颞叶进行tDCS 15分钟的健康个体的厌恶和道德僵化。为了获得对厌恶的全面评估,我们使用了主观的(影响等级),生理的(心率变异性[HRV])和隐含的措施(单词片段完成度),并通过要求参与者对道义论和利他主义进行评估来评估道德判断力。道德基础修正版的道德错误。我们发现阳极和阴极刺激分别增强和减少了自我报告的厌恶,义务论道德和HRV。请注意,对于强迫症(OC)水平较高的个体,这些影响更强。