Background: Disordered speech production, dysarthria, is a common characteristic of the spinocerebellar ataxias (SCAs). Although dysarthric features differ across SCAs, a previous analysis revealed that a combination of regional cerebral blood flow (rCBF) in the left inferior frontal region and the right caudate predicted syllable rate, a pattern reported in normal speakers. This study examined the relationships between primary predictor brain regions and other areas of the brain in three SCA groups. The regions associated with the primary predictors are considered as elements of secondary networks since they are associated with regional speech predictors rather than directly with speech performance.

中文翻译：

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支持脊髓小脑性共济失调语速区域预测因子的网络的基因型差异：初步观察

背景：言语产生障碍、构音障碍是脊髓小脑性共济失调 (SCA) 的常见特征。尽管 SCA 的构音障碍特征不同，但先前的分析表明，左侧下额叶区域和右侧尾状核的局部脑血流量 (rCBF) 的组合预测了音节率，这是正常说话者报告的一种模式。这项研究检查了三个 SCA 组中主要预测大脑区域与大脑其他区域之间的关系。与主要预测器相关联的区域被视为次要网络的元素，因为它们与区域语音预测器相关联，而不是直接与语音性能相关联。