Sequences of the mitochondrial cytochrome c oxidase 1 (COI) gene of 115 Baylisascaris procyonis individuals from 13 U.S. states and 1 Canadian province were obtained from 44 raccoon hosts to assess genetic variation and geographic structure. The maximum genetic distance between individuals was low (1.6%), consistent with a single species. Moderate COI haplotype (h = 0.60) and nucleotide (π = 0.0053) diversity were found overall. Low haplotype diversity was found among samples east of the Mississippi River (h = 0.036), suggesting that historical growth and expansion of raccoon populations in this region could be responsible for high parasite gene flow or a selective sweep of B. procyonis mtDNA. There was low genetic structure (average Φst = 0.07) for samples east of the continental divide, but samples from Colorado showed higher diversity and differentiation from midwestern and eastern samples. There was marked genetic structure between samples from east and west of the continental divide, with no haplotypes shared between these regions. There was no significant isolation by distance among any of these geographic samples. The phylogeographic patterns for B. procyonis are similar to genetic results reported for their raccoon definitive hosts. The phylogeographic divergence of B. procyonis from east and west of the continental divide may involve vicariance resulting from Pleistocene glaciation and associated climate variation.

来自美国 13 个州和加拿大 1 个省的 115 个Baylisascaris procyonis个体的线粒体细胞色素c氧化酶 1 ( COI ) 基因序列来自 44 个浣熊宿主，以评估遗传变异和地理结构。个体之间的最大遗传距离较低（1.6%），与单一物种一致。总体上发现了中等COI单倍型 ( h = 0.60) 和核苷酸 (π = 0.0053) 多样性。在密西西比河以东的样本中发现了低单倍型多样性 ( h = 0.036)，这表明该地区浣熊种群的历史增长和扩张可能是造成高寄生虫基因流或选择性清除的原因B. procyonis mtDNA。大陆分水岭以东的样本具有低遗传结构（平均Φst = 0.07），但来自科罗拉多州的样本与中西部和东部样本显示出更高的多样性和分化。大陆分界东部和西部的样本之间存在显着的遗传结构，这些区域之间没有共享单倍型。这些地理样本中的任何一个都没有明显的距离隔离。B. procyonis的系统地理学模式与其浣熊终宿主报告的遗传结果相似。B. procyonis的系统地理差异 来自大陆分水岭东部和西部的气候变化可能涉及更新世冰川作用和相关气候变化造成的变化。