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A New ε -Truxillic Acid Derivative from the Leaves of Polygala fallax
Chemistry of Natural Compounds ( IF 0.8 ) Pub Date : 2021-05-24 , DOI: 10.1007/s10600-021-03387-x
De-Sheng Ning , Gen Li , Lian-Chun Li , Yu-Xia Fu , Zhi-Qi Zou , Zheng-Hong Pan

A new ε-truxillic acid derivative (1) and five known compounds (2–6) were isolated from the leaves of Palygala fallax. Their structures were elucidated by detailed spectroscopic analysis and comparison with literature data. All compounds were evaluated for their antiradical activities using in vitro DPPH radical scavenging assay. Compounds 5 and 6 showed moderate radical scavenging activity with EC50 value of 54.7 and 39.4 μM.



中文翻译:

远志叶中一种新的ε-硫氰酸衍生物

从Palygala Fallax的叶子中分离出一种新的ε-truxillicacid衍生物(1)和5种已知化合物(2–6)。通过详细的光谱分析和与文献数据的比较阐明了它们的结构。使用体外DPPH自由基清除测定法评估所有化合物的抗自由基活性。化合物56表现出中等的自由基清除活性,EC 50值为54.7和39.4μM。

更新日期:2021-05-24
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