Aims: The unified protocol (UP) is indicated when patients present with co-morbidity, but no studies have previously investigated the effectiveness of the UP with co-morbid health anxiety and depression. Method: An A/B single case design evaluated outcomes for a 27-year-old male presenting with health anxiety and co-morbid depression. Following a 21-day assessment-baseline period containing three sessions, the manualised UP was delivered across a 42-day period containing seven intervention sessions. Four idiographic measures (occurrence and duration of health checking, sleep duration and food intake satisfaction) were collected daily throughout, and two nomothetic measures were collected at four time points. Results: All sessions were attended. Number of health checking episodes reduced from four per day to two per day. A 59 minute per day reduction in time spent health checking occurred, and sleep increased by 100 minutes per night. There was little apparent change in terms of food intake satisfaction. There was a reliable and clinically significant reduction in depression. Discussion: Further testing of the effectiveness of the UP with co-morbid health anxiety and depression in true single case experimental designs is now indicated.

中文翻译：

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治疗共病健康焦虑和抑郁的统一方案的有效性：实证案例研究

目的：统一方案（UP）适用于患有共病的患者，但之前没有研究调查过 UP 对共病健康焦虑和抑郁的有效性。方法：A/B 单病例设计评估了一名 27 岁男性出现健康焦虑和共病抑郁的结果。在包含三个会话的 21 天评估基线期之后，手动 UP 在包含七个干预会话的 42 天期间交付。自始至终每天收集四项具体测量（健康检查的发生和持续时间、睡眠时间和食物摄入满意度），并在四个时间点收集两项常规测量。结果：参加了所有会议。健康检查次数从每天四次减少到每天两次。每天花在健康检查上的时间减少了 59 分钟，每晚的睡眠时间增加了 100 分钟。食物摄入满意度方面几乎没有明显变化。抑郁症有可靠且临床上显着的减少。讨论：现在表明在真正的单例实验设计中进一步测试 UP 与共病健康焦虑和抑郁的有效性。