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A 5-Year Analysis of Physician-Industry Interactions, Physician Gender, and Anti-VEGF Use in US Ophthalmologists
Seminars in Ophthalmology ( IF 1.7 ) Pub Date : 2021-05-23 , DOI: 10.1080/08820538.2021.1922710
Arjun Watane 1 , Meghana Kalavar 1 , Marissa Patel 1 , Nicolas Yannuzzi 1 , Elizabeth A Vanner 1 , Ajay E Kuriyan 2 , Jayanth Sridhar 1
Affiliation  

ABSTRACT

Purpose: To explore physician gender, industry payments, and prescribing habits of anti-vascular endothelial growth factor (VEGF) agents.

Methods: Retrospective review of U.S. ophthalmologists prescribing and receiving industry payments for aflibercept and/or ranibizumab (brand anti-VEGF injections) between August 2013 to December 2017.

Results: Men receiving industry payments were older and had longer post-residency experience than women (both P < .001). Men were more likely to receive industry payments (P = .01), receive >5 payments (P = .003), and receive payments totaling >$1000 (P = .008). Men administered more injections on average than women when receiving >3 industry payments (P < .001) or when receiving >$100 (P < .01). On multivariate analysis, years in practice, male gender, number of payments, and total value of payments were independent factors associated with the number of brand injections administered (all P < .001).

Conclusions: A positive association between industry payments and brand anti-VEGF use was identified, however, causality was not determined. Gender bias may be present in physician-industry relationships.



中文翻译:

美国眼科医生对医生与行业相互作用、医生性别和抗 VEGF 使用的 5 年分析

摘要

目的:探讨抗血管内皮生长因子(VEGF)药物的医生性别、行业支付和处方习惯。

方法:对 2013 年 8 月至 2017 年 12 月期间为阿柏西普和/或雷珠单抗(品牌抗 VEGF 注射剂)开具处方并接受行业付款的美国眼科医生进行回顾性审查。

结果:与女性相比,接受行业付款的男性年龄更大,入驻后经验也更长(均P < .001)。男性更有可能收到行业付款 ( P = .01)、收到超过 5 笔付款 ( P = .003) 以及收到总额超过 1000 美元的付款 ( P = .008)。在接受 >3 次行业付款 ( P < .001) 或接受 > 100 美元 ( P < .01)时,男性平均注射次数多于女性。在多变量分析中,实践年限、男性、支付次数和支付总价值是与品牌注射次数相关的独立因素(所有P < .001)。

结论:确定了行业支付与品牌抗 VEGF 使用之间的正相关关系,但尚未确定因果关系。性别偏见可能存在于医生与行业的关系中。

更新日期:2021-05-23
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