Abstract

Objective

To determine the association of default mode (DMN) and salience (SAL) network connectivity to executive function test performance. We hypothesized that intranetwork connectivity of the DMN and SAL would be uncorrelated to executive function, whereas increased internetwork connectivity would be associated with lower executive function.

Methods

Twelve physically active and healthy young adults (7 females, 5 males; age: 23.41 ± 2.74 years) were recruited for this study. Participants completed resting-state functional magnetic resonance imaging and three executive function tests administered through the NIH Toolbox Cognitive Battery. Demographically-corrected T-scores were calculated from the Flanker Inhibitory Control and Attention Test (FICA), Dimensional Change Card Sort Test (DCCS), and Pattern Comparison Processing Speed Test (PCPS). The relationship between intra- and internetwork connectivity of the DMN and SAL networks and performance.

Results

Independently, the DMN and SAL networks demonstrated weak correlations to DCCS (SAL: r = 0.45, p = 0.14; DMN: r = 0.13, p = 0.69), FICA (SAL r = −0.10, p = 0.95; DMN: r = 0.31, p = 0.33), and PCPS (SAL r = 0.10, p = 0.79; DMN: r = 0.22, p = 0.50). However, connectivity between the SAL and DMN networks demonstrated a moderate correlation to FICA performance (r = −0.61, p = 0.02).

Conclusions

Greater connectivity between the DMN and SAL networks demonstrated the strongest association to attention and inhibitory control performance in physically active, young adults. This relationship suggests greater connectivity of task-negative networks to task-positive networks may interfere with ongoing processing of visuospatial attention and inhibition. Future studies should examine this relationship in athletes who sustain a head injury.

中文翻译：

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A-20默认模式和显着性网络之间的连通性与注意力降低和抑制控制相关

摘要

客观的

确定默认模式（DMN）和显着性（SAL）网络连接与执行功能测试性能的关联。我们假设DMN和SAL的内部网络连接将与执行功能无关，而增加的互联网连接将与较低的执行功能相关。

方法

该研究招募了十二名身体活跃和健康的年轻人（7名女性，5名男性；年龄：23​​.41±2.74岁）。参与者完成了静息状态功能磁共振成像和通过NIH Toolbox认知电池进行的三项执行功能测试。根据弗兰克抑制控制和注意力测试（FICA），尺寸变更卡分类测试（DCCS）和模式比较处理速度测试（PCPS）计算出经过人口统计学校正的T分数。DMN和SAL网络的内部和互连网络连接与性能之间的关系。

结果

独立地，DMN和SAL网络表现出与DCCS的弱相关性（SAL：r = 0.45，p = 0.14; DMN：r = 0.13，p = 0.69），FICA（SAL r = −0.10，p = 0.95; DMN：r = 0.31，p = 0.33）和PCPS（SAL r = 0.10，p = 0.79； DMN：r = 0.22，p = 0.50）。但是，SAL网络与DMN网络之间的连通性与FICA性能表现出中等程度的相关性（r = -0.61，p = 0.02）。

结论

DMN和SAL网络之间的更大连接性表明，在活跃的年轻人中，注意力和抑制控制性能之间的联系最为紧密。这种关系表明，任务阴性网络与任务阳性网络的更大连通性可能会干扰视觉空间注意力和抑制的持续处理。未来的研究应检查头部受伤运动员的这种关系。