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Working towards development of a sustainable brucellosis control programme, the Azerbaijan example
Research in Veterinary Science ( IF 2.4 ) Pub Date : 2021-05-21 , DOI: 10.1016/j.rvsc.2021.05.014
Masud Khatibi 1 , Galib Abdulaliyev 2 , Anar Azimov 1 , Rita Ismailova 3 , Sabina Ibrahimov 4 , Mazahir Shikhiyev 1 , Dilgam Agalarov 1 , Tural Seyidov 1 , Asaf Omarov 5 , Chichak Suleymanova 2 , Shalala Zeynalova 6 , Rakif Abdullayev 7 , Aytan Hajiyeva 8 , Ron Jackson 9
Affiliation  

Brucellosis caused by Brucella abortus and Brucella melitensis is endemic in the Republic of Azerbaijan but a complex mix of fiscal, political and technical constraints has impeded regulatory authority decision making for adoption of a sustainable national control programme. This paper reports a series of epidemiologic studies of the disease in animals and humans which we conducted between 2009 and 2020. A preliminary study and a subsequent larger study using vaccination of all non-pregnant female sheep and goats of breeding age and all females between 3 and 8 months with conjunctival Rev1 vaccine both recorded significant reduction in small ruminant seroprevalences. A case control study of winter pasture flocks found many case and control farmers used raw milk to make dairy products for sale, ate fresh cheese and sold dairy products in unregulated markets. Almost all farmers expressed willingness to pay a portion of the costs associated with elimination of brucellosis from their flocks. A pilot human study in 2009 led to a large study in 2017 which recorded an overall seroprevalence of 8.1% in humans. Persons in farm related occupations were at greater risk than urban persons and males were more likely to be seropositive than females. Risk factors included keeping small ruminants, using raw milk cheese and slaughtering animals whereas having heard education information about brucellosis and vaccinating against brucellosis were protective.



中文翻译:

努力制定可持续的布鲁氏菌病控制计划,阿塞拜疆的例子

流产布鲁氏melutensis布鲁氏菌引起的布鲁氏菌病在阿塞拜疆共和国是地方病,但财政,政治和技术方面的限制因素复杂,阻碍了监管机构为采用可持续的国家控制计划而做出的决策。本文报告了我们在2009年至2020年之间对动物和人类疾病进行的一系列流行病学研究。初步研究和随后的较大研究是对所有未怀孕的成年雌性绵羊和山羊以及所有3岁之间的雌性疫苗进行疫苗接种结膜Rev1疫苗的8个月和8个月的双反刍动物血清阳性率均显着降低。一项针对冬季牧场群的病例对照研究发现,许多病例和对照农民都使用原奶制作待售的乳制品,吃了新鲜的奶酪,并在不受管制的市场上出售了乳制品。几乎所有农民都表示愿意支付与消除家禽中的布鲁氏菌病相关的部分费用。2009年进行的一项试点人体研究导致了2017年的一项大规模研究,该研究表明人类的总体血清阳性率为8.1%。从事农业相关工作的人比城市人面临的风险更大,而男性比女性更容易出现血清反应阳性。风险因素包括保持小反刍动物,使用生乳奶酪和宰杀动物,而听说过有关布鲁氏菌病的教育信息和接种预防布鲁氏菌病的疫苗是有保护作用的。从事农业相关工作的人比城市人面临的风险更大,而男性比女性更容易出现血清反应阳性。风险因素包括保持小反刍动物,使用生乳奶酪和宰杀动物,而听说过有关布鲁氏菌病的教育信息和接种预防布鲁氏菌病的疫苗是有保护作用的。从事农业相关工作的人比城市人面临的风险更大,而男性比女性更容易出现血清反应阳性。风险因素包括保持小反刍动物,使用生乳奶酪和宰杀动物,而听说过有关布鲁氏菌病的教育信息和接种预防布鲁氏菌病的疫苗是有保护作用的。

更新日期:2021-05-25
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