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Cover Feature: Polydopamine-Mediated Surface Functionalization of Exosomes (ChemNanoMat 6/2021)
ChemNanoMat ( IF 3.8 ) Pub Date : 2021-05-22 , DOI: 10.1002/cnma.202100154
Chenyu Wang 1 , Kenta Kimura 1 , Jincai Li 1 , Joseph J. Richardson 1 , Mitsuru Naito 2 , Kanjiro Miyata 1 , Takanori Ichiki 1 , Hirotaka Ejima 1
Affiliation  

Exosomes were non-covalently functionalized using the self-polymerization of dopamine and subsequent PEGylation via Thiol-Michael addition. This rapid and versatile exosome coating method improved the colloidal stability of exosomes and endowed them with tunable fluorescence and coating thickness. Collectively, this aggregation-free non-covalent coating approach expands the potential of exosomes in various applications without requiring complex equipment or reagents. More information can be found in the Communication by Hirotaka Ejima et al.
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中文翻译:

封面特征:聚多巴胺介导的外泌体表面功能化 (ChemNanoMat 6/2021)

外泌体通过多巴胺的自聚合和随后通过硫醇-迈克尔加成的聚乙二醇化进行非共价功能化。这种快速且通用的外泌体包被方法提高了外泌体的胶体稳定性,并赋予它们可调的荧光和包被厚度。总的来说,这种无聚集的非共价涂层方法扩展了外泌体在各种应用中的潜力,而无需复杂的设备或试剂。更多信息可以在 Hirotaka Ejima 等人的通讯中找到。
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更新日期:2021-06-04
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