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Molecular and pharmacological characterization of biogenic amine receptors from the diamondback moth, Plutella xylostella
Pest Management Science ( IF 4.1 ) Pub Date : 2021-05-18 , DOI: 10.1002/ps.6481
Tiansheng Liu, Xue Zhan, Yuan Yu, Shaozhen Wang, Cong Lu, Guifang Lin, Xiangyu Zhu, Weiyi He, Minsheng You, Shijun You

Insect biogenic amines play important roles in mediating behavioral and physiological processes. They exert their effects by binding to biogenic amine receptors (BARs), which are specific receptor proteins in the G-protein-coupled receptor superfamily. BAR genes have been cloned and characterized from multiple model insects, including Drosophila melanogaster, Anopheles gambiae, Bombyx mori, Apis mellifera and Tribolium castaneum. However, relatively little work has addressed the molecular properties, expression profiles, and pharmacological characterization of BARs from other insects, including important pests.

中文翻译:

小菜蛾生物胺受体的分子和药理学特征,小菜蛾

昆虫生物胺在调节行为和生理过程中起重要作用。它们通过与生物胺受体 (BAR) 结合来发挥作用,BAR 是 G 蛋白偶联受体超家族中的特异性受体蛋白。BAR 基因已从多种模式昆虫中克隆和表征,包括黑腹果蝇冈比亚按蚊家蚕意大利蜜蜂栗谷赤。然而,相对较少的工作涉及来自其他昆虫(包括重要害虫)的 BAR 的分子特性、表达谱和药理学特征。
更新日期:2021-05-18
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