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Negative symptoms in schizophrenia: reconsidering evidence and focus in clinical trials
The British Journal of Psychiatry ( IF 10.5 ) Pub Date : 2021-05-19 , DOI: 10.1192/bjp.2021.66
Lisette van der Meer 1 , Stefan Kaiser 2 , Stynke Castelein 3
Affiliation  

Negative symptoms of schizophrenia have been documented in the literature for over a century. Nevertheless, research has not convincingly produced effective interventions for their treatment. We propose to re-analyse currently published evidence on treatment of negative symptoms, using narrower definitions for symptom dimensions, to better understand what works for whom.



中文翻译:

精神分裂症的阴性症状:重新考虑临床试验的证据和重点

精神分裂症的阴性症状已经在文献中记录了一个多世纪。然而,研究并没有令人信服地产生有效的治疗干预措施。我们建议重新分析目前发表的关于治疗阴性症状的证据,使用更窄的症状维度定义,以更好地了解什么对谁有效。

更新日期:2021-06-28
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