This paper comments on the article “On the effect of excessive solar exposure on human skin: Confocal Raman spectroscopy as a tool to assess advanced glycation end products” by A.F.M. Pereira et al. The authors apply Raman spectroscopy to detect advanced glycation end products in human skin and to classify skin tissues by means of their Raman spectra. Despite a similarity between skin tissues spectra and AGEs spectra, some measurements of AGEs in the skin based on the previously validated techniques are required to prove AGEs presence. To confirm the possibility to discriminate skin tissues using Raman spectra analysis the authors should provide additional data regarding the obtained discriminating models.

本文评论AFM Pereira等人的文章“过度日光照射对人体皮肤的影响：共聚焦拉曼光谱法作为评估先进糖基化终产物的工具”。作者应用拉曼光谱法检测人类皮肤中晚期糖基化终产物，并通过其拉曼光谱对皮肤组织进行分类。尽管皮肤组织光谱和AGEs光谱之间存在相似之处，但仍需要基于先前验证的技术对皮肤中的AGEs进行一些测量，以证明AGEs的存在。为了确定使用拉曼光谱分析来区分皮肤组织的可能性，作者应提供有关所获得的区分模型的其他数据。