Biological Effect of Silver-modified Nanostructured Titanium Dioxide in Cancer.,Cancer Genomics & Proteomics

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Biological Effect of Silver-modified Nanostructured Titanium Dioxide in Cancer.
Cancer Genomics & Proteomics ( IF 2.5 ) Pub Date : 2021-5-18 , DOI: 10.21873/cgp.20269
Nefeli Lagopati _{1,

2,

3} , Athanassios Kotsinas ₁ , Dimitris Veroutis _{1,

3} , Konstantinos Evangelou ₁ , Angelos Papaspyropoulos _{1,

3} , Michalis Arfanis ₄ , Polycarpos Falaras ₄ , Paraskevi V Kitsiou ₅ , Ioannis Pateras ₁ , Anna Bergonzini ₆ , Teresa Frisan ₆ , Spyridon Kyriazis ₁ , Dimitrios S Tsoukleris _{2,

7} , Effie-Photini C Tsilibary ₈ , Maria Gazouli ₉ , Evangelia A Pavlatou ₁₀ , Vassilis G Gorgoulis _{3,

11,

12,

13}

Affiliation

Laboratory of Histology-Embryology, Molecular Carcinogenesis Group, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Laboratory of General Chemistry, School of Chemical Engineering, National Technical University of Athens, Zografou Campus, Athens, Greece.
Biomedical Research Foundation Academy of Athens, Athens, Greece.
Institute of Nanoscience and Nanotechnology, Laboratory of Nanotechnology Processes for Solar Energy Conversion and Environmental Protection, National Centre for Scientific Research "Demokritos", Athens, Greece.
Institute of Biosciences and Applications, Laboratory of Biochemistry/Cell & Matrix Pathobiology, National Centre for Scientific Research "Demokritos", Athens, Greece.
Umeå Centre for Microbial Research (UCMR), Department of Molecular Biology, Umeå University, Umeå, Sweden.
NanoViis Company, Athens, Greece.
Department of Neuroscience, University of Minnesota, Minneapolis, MN, U.S.A.
Department of Basic Medical Sciences, Laboratory of Biology, Faculty of Medicine, School of Health Science, National and Kapodistrian University of Athens, Athens, Greece.
Laboratory of General Chemistry, School of Chemical Engineering, National Technical University of Athens, Zografou Campus, Athens, Greece;
Laboratory of Histology-Embryology, Molecular Carcinogenesis Group, Medical School, National and Kapodistrian University of Athens, Athens, Greece;
Faculty of Biology, Medicine and Health Manchester Cancer Research Centre, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, U.K.
Center for New Biotechnologies and Precision Medicine, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

Nanomedicine is a promising scientific field that exploits the unique properties of innovative nanomaterials, providing alternative solutions in diagnostics, prevention and therapeutics. Titanium dioxide nanoparticles (TiO₂ NPs) have a great spectrum of photocatalytic antibacterial and anticancer applications. The chemical modification of TiO₂ optimizes its bioactive performance. The aim of this study was the development of silver modified NPs (Ag/TiO₂ NPs) with anticancer potential.

中文翻译：

银改性纳米结构二氧化钛在癌症中的生物学效应。

纳米医学是一个很有前途的科学领域，它利用创新纳米材料的独特特性，为诊断、预防和治疗提供替代解决方案。二氧化钛纳米粒子（TiO ₂ NPs）具有广泛的光催化抗菌和抗癌应用。TiO ₂的化学修饰优化了其生物活性性能。本研究的目的是开发具有抗癌潜力的银改性纳米颗粒（Ag/TiO ₂ NPs）。

更新日期：2021-05-20

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