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Green Synthesis of Novel Azo-Linked 2-Aryl-Quinazolinones Using Fe 3 O 4 @SP@TA Nanoparticle
Journal of Cluster Science ( IF 2.8 ) Pub Date : 2021-05-17 , DOI: 10.1007/s10876-021-02021-8
Abdolrahman Keyhani , Mohammad Nikpassand , Leila Zare Fekri , Hassan Kefayati

Tannic acid‐functionalized silica‐coated Fe3O4 nanoparticles (Fe3O4@SP@TA) were synthesized and characterized by X-ray spectroscopy (EDX), X-ray powder diffraction (XRD), field emission scanning electron microscope (FE-SEM), transmission electron microscope (TEM), vibrating sample magnetometry (VSM) and Fourier transform infrared spectroscopy (FT-IR). Fe3O4@SP@TA supply an eco-friendly procedure for the synthesis of some novel 2-aryl-quinazolinones through one-pot reaction of various synthetized azo-linked benzaldehyes, isatoic anhydride and glycine in accordance with green chemistry rules. These compounds were obtained in high yields and short reaction times. The catalyst could be easily recovered and reused for six cycles with almost consistent activity. The structures of the synthesized azo-linked 2-aryl-quinazolinone compounds were confirmed by 1H NMR, 13C NMR and FTIR spectral data and elemental analyses.



中文翻译:

Fe 3 O 4 @ SP @ TA纳米粒子绿色合成新型偶氮连接的2-芳基-喹唑啉酮

合成了鞣酸官能化的二氧化硅包覆的Fe 3 O 4纳米颗粒(Fe 3 O 4 @ SP @ TA),并通过X射线光谱(EDX),X射线粉末衍射(XRD),场发射扫描电子显微镜( FE-SEM),透射电子显微镜(TEM),振动样品磁力分析(VSM)和傅立叶变换红外光谱(FT-IR)。铁3 O 4@ SP @ TA根据绿色化学法则,通过各种合成的偶氮连接的苯甲醛,等位酸酐和甘氨酸的一锅反应,为某些新型的2-芳基-喹唑啉酮的合成提供了一种环境友好的程序。这些化合物以高收率和短反应时间获得。该催化剂可以很容易地回收并以几乎恒定的活性重复使用六个循环。合成的偶氮连接的2-芳基-喹唑啉酮化合物的结构通过1 H NMR,13 C NMR和FTIR光谱数据以及元素分析得到证实。

更新日期:2021-05-17
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