MRI's transverse relaxation time (T₂) is sensitive to tissues' composition and pathological state. While variations in T₂ values can be used as clinical biomarkers, it is challenging to quantify this parameter in vivo due to the complexity of the MRI signal model, differences in protocol implementations, and hardware imperfections. Herein, we provide a detailed analysis of the echo modulation curve (EMC) platform, offering accurate and reproducible mapping of T₂ values, from 2D multi-slice multi-echo spin-echo (MESE) protocols.

中文翻译：

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用于准确且可重复地评估横向 (T2) 弛豫时间的定量平台

MRI的横向弛豫时间（T ₂）对组织成分和病理状态敏感。虽然T ₂值的变化可用作临床生物标志物，但由于 MRI 信号模型的复杂性、协议实现的差异和硬件缺陷，在体内量化该参数具有挑战性。在这里，我们提供了回波调制曲线 (EMC) 平台的详细分析，提供了来自 2D 多层多回波自旋回波 (MESE) 协议的T _{2值的准确且可重复的映射。}