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Sex Effects on Mirror Overflow during Finger Tapping in Children with ADHD
Journal of the International Neuropsychological Society ( IF 2.6 ) Pub Date : 2021-05-17 , DOI: 10.1017/s1355617721000576
C Chen 1 , K S Rosch 1, 2, 3 , K E Seymour 1, 3, 4 , D Crocetti 1 , E M Mahone 2, 3 , S H Mostofsky 1, 3, 5
Affiliation  

Objectives:

The presence of excessive mirror overflow in children with Attention Deficit/Hyperactivity Disorder (ADHD) is discussed in numerous published reports. These reports, however, include a limited age range in their samples. The objective of this study is to examine the effects of diagnosis and sex on mirror overflow and standard deviation (SD) of tap time in children with and without ADHD across a larger age range (5–12 years) of children.

Methods:

One-hundred and forty-eight children with ADHD and 112 age- and sex-matched typically developing (TD) children completed a finger sequencing task. Mirror overflow, SD of tap time, and mean tap time were measured using finger twitch transducers.

Results:

Results reveal a significant diagnostic effect on mirror overflow such that boys and girls with ADHD demonstrate increased overflow compared to same-sex TD children. Boys with ADHD demonstrated more variable tap times compared to TD boys; no diagnostic effect was observed in the girls.

Conclusions:

Boys with ADHD exhibit anomalous motor variability; girls with ADHD show similar levels of variability as TD girls. Boys and girls with ADHD exhibit similar levels of excessive mirror overflow. This lack of sex differences on mirror overflow is distinct from reports finding sex effects on overflow and could result from an examination of a broader age range than is included in prior reports. Adolescent data would provide a greater understanding of the trajectory of anomalous mirror overflow across development. Examination of functional and structural connectivity would expand the current understanding of the neurobiological foundation of motor overflow.



中文翻译:

多动症儿童敲击手指时性别对镜子溢出的影响

目标:

许多已发表的报告都讨论了注意力缺陷/多动障碍 (ADHD) 儿童过度镜像溢出的问题。然而,这些报告的样本年龄范围有限。本研究的目的是在更大年龄范围(5-12 岁)的儿童中检查诊断和性别对患有和不患有 ADHD 的儿童的镜像溢出和点击时间的标准差 ( SD ) 的影响。

方法:

148 名多动症儿童和 112 名年龄和性别匹配的正常发育 (TD) 儿童完成了一项手指测序任务。使用手指抽搐传感器测量镜子溢出、敲击时间的标准差和平均敲击时间。

结果:

结果显示对镜子溢出有显着的诊断作用,因此与同性 TD 儿童相比,患有 ADHD 的男孩和女孩表现出更多的溢出。与 TD 男孩相比,患有 ADHD 的男孩表现出更多可变的敲击时间;在女孩中没有观察到诊断效果。

结论:

患有多动症的男孩表现出异常的运动变异性;患有 ADHD 的女孩表现出与 TD 女孩相似的变异水平。患有多动症的男孩和女孩表现出相似程度的过度镜像溢出。镜像溢出缺乏性别差异不同于发现溢出对性别影响的报告,并且可能是由于对比先前报告中包含的更广泛年龄范围的检查所致。青少年数据将有助于更好地了解异常镜像溢出在整个发展过程中的轨迹。功能和结构连通性的检查将扩展当前对运动溢出的神经生物学基础的理解。

更新日期:2021-05-17
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